http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20110044905-A
Outgoing Links
| Predicate | Object |
|---|---|
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2863 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6809 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-53 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate | 2009-08-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationDate | 2011-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20110044905-A |
| titleOfInvention | Methods and systems for predicting cell response to therapeutic agents |
| abstract | The present invention provides a method of treating a patient and includes a method of predicting the response of cells such as tumor cells to treatment with a therapeutic agent. The method comprises measuring, in a sample of cells, the level of one or more components of the cell network and calculating a network activation state (NAS) or network inhibition state (NIS) for the cell using a computational model of the cell network. do. The response of cells to treatment is predicted based on the calculated NAS or NIS values. The present invention also includes methods for predicting the response of cells, wherein the calculation of NAS or NIS values for cells (eg, tumor cells) is combined with the use of statistical classification algorithms. Biomarkers are also provided that predict response to treatment with therapeutic agents that target components in the ErbB signaling pathway. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101430309-B1 |
| priorityDate | 2008-08-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 944.