| abstract |
D-Ala 7 -Angiotensin- (1-7) (A-779) and homologues and derivatives, D-Pro 7 -Angiotensin- (1-7) and homologues and derivatives, or Ang- (1-7) homologs or derivatives At the technical level of formulation, application or product of arterial hypertension and other cardiovascular diseases and complications thereof, wounds, burns, erythema, tumors, diabetes, sperm mobility, kidney disease, gastrointestinal and gynecological diseases, angiogenesis, angioplasty, There is no disclosure of use as a ligand for cyclodextrins, liposomes, biodegradable polymers and derivatives thereof, or G-protein-coupled receptor MAS in the study or treatment of alopecia and blood diseases. This characterizes the present invention as a more effective option for the study and treatment of pathologies associated with or without the receptor. The present invention features two different techniques: molecular encapsulation of peptide angiotensin- (1-7) and its analogs and derivatives in cyclodextrins and microencapsulation in biodegradable polymers and liposomes. The invention is also characterized by an increase in the peptides and their analogs and derivatives using the formulations of the invention. |