| abstract |
The present invention provides a monoclonal antibody that specifically recognizes CD27 containing an O-linked sugar chain to which galactose is not bound and binds to the extracellular region, and a method of using the same. According to the present invention, a monoclonal antibody or the antibody fragment which specifically recognizes CD27 including an O-linked sugar chain to which galactose is not bound and binds to the extracellular domain, a hybridoma producing the antibody, DNA encoding the antibody, a vector comprising the DNA, a transformant obtained by transforming the vector, an antibody or a method for producing the antibody fragment using the hybridoma or transformant, and the antibody or A diagnostic or therapeutic drug for a disease involving CD27 comprising an antibody fragment as an active ingredient can be provided. |