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filingDate 2009-05-11-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_531297914cf3c4c373cfaa91512ac440
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publicationDate 2011-04-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20110036001-A
titleOfInvention Production method of milk fraction rich in secretory immunoglobulins
abstract The present invention relates to a method for producing a composition rich in secretory IgA (S-IgA) by fractionating milk containing S-IgA. Such compositions are particularly useful for the treatment and / or prevention of infections and / or inflammations of mucosal surfaces, such as, for example, the gastrointestinal tract, genitourinary, airways, nasal or oral cavity, the treatment and / or prevention of obesity and related diseases, or food allergies. It may be used in subjects in need of such treatment for the treatment and / or prevention of. Briefly stated, the present invention provides a method for producing a secreted immunoglobulin A-rich milk fraction using one or more microporous membrane filtration steps. Preferred protocols of the present invention include degreasing, microfiltration and ultrafiltration-enrichment through multiple diafiltration cycles. In addition to achieving high yields unexpectedly, the methods of the present invention provide particular advantages in terms of scalability, existing diary factory applicability and control of process parameters affecting S-IgA quality and stability.
priorityDate 2008-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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