http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20110034116-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cf92f6c5ea033eae1b28d2411f9c1335 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-54 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-6481 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P9-00 |
filingDate | 2009-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7372ef1021b1b7226ef62be654e34f43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd25fb1ae13fcab7db828e59bf60d1ba http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e497bf77cb5d31e2d8c8f69c38c66ad2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9f95fe656d2d72c1eaef2760b9f4040 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8032154514ee36fc826921dfa186623b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_798863e23f0999af6fda64fbf8e50344 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd50f22078887679418063f575b327ad http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5a19a354458f3af2a071f45f6b21434d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_67349a123794f8a95ac4cc57870d1403 |
publicationDate | 2011-04-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20110034116-A |
titleOfInvention | Selectivity of Fatty Acid Substitution of Phospholipids by Immobilized Phospholipase A2 and Methods for Improving Productivity |
abstract | The present invention relates to a method for biosynthesis of phospholipids substituted with phospholipids by phospholipid A2 (PLA2) as a substrate, and the enzyme selectivity and productivity of fatty acid substitution sites and fatty acid types. It relates to a method of improving the yield of conversion to the phospholipid of the desired structure.n n n In order to achieve the above object, the present invention changes the order of preparation of the immobilized enzyme and the addition order of the cofactor, the dissolution order of the substrate, to control the interaction between the substrate molecules and the immobilized enzyme, the operation of the reactor and the like. It was.n n n The present invention comprises a first step of immobilizing phospholipase A2 (PLA2) on a silica carrier; A second step of mixing phospholipids, fatty acids, cofactors, and the like with the immobilized enzyme in a selective order; A third step of replacing the mixed solution with a phospholipid fatty acid at a constant temperature; It provides a method for producing a phospholipid, characterized in that it comprises a fourth step of recovering the fatty acid that has not reacted with the immobilized enzyme in the reacted liquid and isolating the phospholipid in which the fatty acid is optionally substituted ([FIG. 1]).n n n As a result, a particular effect of the present invention is to improve the yield and productivity of conversion to the phospholipids of the desired structure by selectively controlling the substitution sites and fatty acid types of fatty acids. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101446475-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20220063416-A |
priorityDate | 2009-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 296.