http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20110027616-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69f43505d1b3ec31c224b32b5d1ec4e2 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-75 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-2878 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L1-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395 |
| filingDate | 2010-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b2a38adc99ad58756e360b20730ff1c3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2125503dea9b01a99487770a390b548c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_834136a81d002beda6aa863dc3811215 |
| publicationDate | 2011-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20110027616-A |
| titleOfInvention | Composition for the prevention or treatment of metabolic disorders comprising an anti-4-1ＢＢ antibody |
| abstract | The present invention relates to a novel use of the anti- 4-1BB antibody, and more particularly, the present invention for the prevention or treatment of metabolic diseases comprising an anti-antigenic 4-1BB antibody having specificity to the 4-1BB molecule as an active ingredient It relates to a composition. When administered to an animal model induced obesity, the anti- 4-1BB antibody according to the present invention has the effect of reducing weight and weight of adipose tissue in the body, and improving the insulin resistance and glucose tolerance disorder induced by obesity As well as having an excellent effect of reducing the total cholesterol content, triglyceride content and free fatty acid content ratio, the composition of the present invention comprising an anti-4-1BB antibody is obesity, type 2 diabetes mellitus accompanied with abnormal lipid metabolism There is an effect that can be used as a pharmaceutical composition and a functional food composition that can prevent, treat or ameliorate metabolic diseases such as hyperlipidemia, hypercholesterolemia, arteriosclerosis and fatty liver. |
| priorityDate | 2009-09-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 274.