abstract |
The present invention relates to a method for preparing a drug product comprising two or more separate members of a polyclonal protein, eg, a polyclonal antibody, wherein each separate member is an independent Expressed by a cell population. The method of the invention comprises at least a starting step of individually culturing cell populations expressing distinct members of the polyclonal protein. Individual cell populations, or proteins expressed by these individual cell populations, are combined at an upstream later point or downstream treatment to produce one drug product comprising distinct members of the polyclonal protein. Let's do it. |