abstract |
The present invention relates to a functional food containing a natural substance-derived estrogen agonist, purified from silkworm pupa extract. In the present invention, the estrogen action of the substance isolated and purified according to the present invention from the water-soluble extract of silkworm pupa is confirmed through in vitro and in vivo experiments. Based on these results, in the present invention, a material obtained by fractionating a silkworm pupae with water from a water-soluble silkworm pupae extract at room temperature through a sulfonic acid type strong acid cation exchange resin (Dowex ™ 50W-8X (H +)) column and washing with distilled water is an active ingredient. Functional foods containing are provided. In the examples of the present invention, it is confirmed that the estrogen agonist of the present invention is useful as an estrogen replacement material such as phytoestrogen. |