abstract |
The present invention provides an immunogenic composition comprising a Streptococcus pneumoniae antigen and an adjuvant composition comprising an oil-in-water emulsion, wherein the oil-in-water emulsion in the immunogenic composition of the present invention is 0.5-per human dose. 10 mg of metabolizable oil, 0.5-11 mg of tocol and 0.1-4 mg of emulsifier. |