abstract |
The present invention relates to a pharmaceutical composition for preventing and treating cancer comprising iris ( Iris nertschinskia ) extract as an active ingredient, and a food composition for preventing and inhibiting cancer comprising the same. The composition comprising the iris extract according to the present invention induces cell death through p53 and caspase activity in cancer cells in which p53 is normal, and induces cell death through caspase activity in cancer cells in which p53 is abnormal. Therefore, the iris extract according to the present invention induces apoptosis of cancer cells and has the effect of preventing, inhibiting and treating cancer.n n n n Iris, cancer, p53, caspase, apoptosis |