abstract |
The present invention relates to a composition for regulating immune response comprising an expression construct of an anti-sense nucleotide sequence complementary to an NDRG2 (N-Myc downstream-regulated gene 2) protein coding nucleotide sequence or an NDRG2 protein coding nucleotide sequence. It is about. The present invention provides a composition that can enhance the immune response by inducing the expression of NDRG2 protein in immune cells, and on the contrary, inhibits the expression of NDRG2 protein. Therefore, according to the present invention, the immune response can be regulated by regulating the expression of NDRG2 in immune cells. |