http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20100137458-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 |
| filingDate | 2009-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_87bcea3532974e6fc9947c77445a53b3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b491aa7c5606f63db96a007dbea2676f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea41b995ce9b69b083a6e18136f2cd3f |
| publicationDate | 2010-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20100137458-A |
| titleOfInvention | Fluorescence-based Assay to Detect Sodium / Calcium Exchanger (NCC) ＂Reverse Mode＂ Regulatory Compound |
| abstract | The vehicle is a new target class with huge potential, providing scientific and economic opportunities. Sodium / calcium exchanger is an important mechanism for removing Ca 2 + from diverse cells. Sodium / calcium exchanger is of the heart, and pushes the Ca 2 + entered through Ca 2 + channel initiate contraction, Na + enters the heart cell. It is of great importance to identify compounds that modulate the calcium outward transport activity of the sodium / calcium exchanger (forward mode) as well as the calcium transport activity of the sodium / calcium exchanger (reverse mode). The present invention relates to fluorescence based assays for detecting NCX "reverse mode" modulating compounds. The present invention also relates to a kit of parts comprising the cells primers for NCX and to the use of a kit of parts for testing the compound for activity as an agent or antagonist of NCX. |
| priorityDate | 2008-03-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 144.