abstract |
The present invention relates to adefovir difficile hemisevacinate, which is a novel acid addition salt of adefovir dipivoxil, and a pharmaceutical composition comprising the same. Adefovir difficile hemicevacinate according to the present invention is excellent in stability, nonhygroscopicity and solubility, and thus can be effectively used in pharmaceutical compositions for the treatment of HIV and hepatitis B virus infection. |