http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20100130586-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2eb84eabb33a184477bc90767646d589 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D231-44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-10 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01P1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A01N43-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D231-44 |
| filingDate | 2008-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fced6e3b079a4fdbcc4c984e4000ecc4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5083ea5f117935f75b947d52a7f636a3 |
| publicationDate | 2010-12-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20100130586-A |
| titleOfInvention | Process for manufacturing fipronil and its analogs |
| abstract | The present invention provides 5-amino-1- (2,6-dichloro-4- (trifluoromethyl) phenyl) -4- (trifluoromethyl-thio)-useful as an intermediate of the insect repellent fipronil. 1 H -pyrazole-3-carbonitrile (5-amino-1- (2,6-dichloro-4- (trifluoromethyl) phenyl) -4- (trifluoromethyl-thio) -1 H- pyrazole-3-carbonitrile) ( Hereinafter, a novel and efficient process for preparing a compound of formula I) and 5-amino-3-cyano-1- (2,6-dichloro-4-trifluoromethylphenyl) -4-trifluoromethyl sulfinyl It relates to a process for producing pyrazole (5-amino-3-cyano-1- (2,6-dichloro-4-trifluoromethylphenyl) -4-trifluoromethyl sulfinylpyrazole) (hereinafter referred to as a compound of formula II or pipenonyl). In one aspect, a) reacting CF 3 S (= 0) ONa with a compound of Formula III in the presence of a reducing / halogenating agent; And b) oxidizing the compound of formula (I) obtained in step a) in the presence of a selective oxidant which selectively oxidizes (I) to the corresponding sulfoxide, fipronil, under suitable conditions. Process is provided. In certain exemplary embodiments, the selective oxidant is MHSO 5 , where M is an alkali metal cation. |
| priorityDate | 2007-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 92.