abstract |
Compounds of formula (I) in free or salt or solvate form are useful for the treatment of diseases mediated by ALK-5 and / or ALK-4 receptors. Pharmaceutical compositions containing the compounds and methods of making the compounds are also described. <Formula I> In formula, X, R < 1> , R < 2> , R < 3> and R < 4> have the meaning as shown here. |