abstract |
The present invention relates to a nucleic acid aptamer capable of specifically recognizing and binding to pancreatic cancer cells or tissues and uses thereof. The nucleic acid aptamer according to the present invention can be usefully used as a composition for diagnosing and treating pancreatic cancer by specifically binding to pancreatic cancer cells or tissues without binding to normal pancreatic tissue. In addition, the nucleic acid aptamer according to the present invention can detect not only Capan-1, which is a late pancreatic cancer cell line, but also Panc-1, an early pancreatic cancer cell line, and can be used to diagnose early pancreatic cancer, thereby contributing to increasing the survival rate of pancreatic cancer patients. have. |