| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3af1092242c462ea0b3aff3c152ef0c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_d3163957db744d0171ae3ff8ab14f0d5 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2820-002
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2511-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-70
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-16 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-63
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N9-48 |
| filingDate |
2009-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6427511da67c19e318512c18f7f3838f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ed0fbc4a7d2337de0038adcd2fe4c0b9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9cb0befa131f781c10f5fc6844d9c705
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3a82e1101a18bde68be60baeda079bd9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2041a30599bb93ff483793dd365878aa |
| publicationDate |
2010-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20100126969-A |
| titleOfInvention |
Codon-optimized genes encoding proteins with human deformillase activity |
| abstract |
The present invention provides a novel gene encoding a protein having human deformillase activity as a codon optimized novel gene. The present invention also provides a vector comprising the gene, a transformant obtained by transforming an Escherichia genus strain with the vector, and a protein having human deformillase activity by culturing the transformant. It provides a method of manufacturing.n n n The gene obtained according to the present invention is a gene obtained by lowering GC content in a gene encoding a protein having human deformillase activity and performing codon optimization by substituting a rare codon, and in an Escherichia genus strain When expressed, proteins having human deformillase activity can be expressed with high efficiency. Therefore, since the host cell transformed with the vector containing the gene can obtain a large amount of hPDF, it can be usefully used for screening an anticancer agent targeting human deformillase. |
| priorityDate |
2009-05-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |