| abstract |
The present invention provides a novel benzodiazepine compound having excellent selectivity with other K + channels and having a strong I Kur current or Kv1.5 channel blocking action. The benzodiazepine compound of the present invention is represented by the formula (1). <Formula 1> [Wherein, R 1 , R 2 , R 3 , and R 4 are each independently hydrogen or lower alkyl; R 2 and R 3 may combine to form lower alkylene; A 1 is lower alkylene which may be substituted with one or more hydroxy; R 5 is a group represented by the following formula (Wherein R 6 and R 7 are each independently hydrogen or an organic group; X A and X B are each independently a bond, lower alkylene, etc.)] |