abstract |
The method of the present invention performs in vitro liver, intestinal and / or transgenic enzyme analysis with selected phytophytologic materials for humans and animals of various species to produce metabolites for a series of species, such as humans and animals. Steps. Subsequently, a comparison is made between species obtained from human in vitro studies and species obtained from animal in vitro studies to determine the closest pair. The animal with the closest pair is then used for in vivo studies. If there is a pair between animal in vivo and human in vivo results, the paired species are isolated or synthesized and then tested to determine the suitability of the paired species as a therapeutic drug. |