| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_5b65747ed78f05dd9ebe107b50ce2855 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-454
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2009
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2027
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2054
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-143
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-146
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1635
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-1652
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-225 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-30 |
| filingDate |
2005-10-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ca6328f14a908768534f4c58c649747
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a4a5e2816e78c56f212e63f9b29d642d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e7747ab751b7be5ad702dc942492d82 |
| publicationDate |
2010-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20100120244-A |
| titleOfInvention |
Solid preparations with improved solubility and stability and methods for their preparation |
| abstract |
The present invention relates to a solid preparation having improved solubility while maintaining the stability of the preparation by adding a formulation to a poorly water-soluble chemical substance as a medicinal active ingredient. Specifically, it is a solid preparation comprising a poorly water-soluble chemical substance, a water-soluble polymer substance and an inorganic porous substance as a medicinal active ingredient, (1) the poorly water-soluble chemical substance forms a solid dispersion together with the water-soluble polymer substance, (2 (3) The water-soluble polymer material forming the solid dispersion is in the form of microflakes, and (3) the water-soluble polymer material in the form of the microflakes is adsorbed and / or adhered to the surface of the inorganic porous material. It is a solid formulation with improved solubility. These solid preparations can be prepared by stirring and mixing a solution obtained by dissolving a poorly water-soluble chemical substance and a water-soluble high molecular substance as a pharmaceutically active ingredient in an organic solvent, followed by granulation and drying. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2016006862-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2019135420-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013089479-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20160005971-A |
| priorityDate |
2004-10-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |