| abstract |
The present invention relates to compounds of formula (I). Formula I Substituents in the above formula are as described in claim 1. The compounds of formula (I) of the present invention are modulators for amyloid beta and thus diseases associated with brain deposition of β-amyloid, in particular Alzheimer's disease, and cerebral amyloid angiopathy, Dutch amyloidogenic hereditary cerebral hemorrhage (HCHWA-D), multiple infarction It has been found to be useful for the treatment and prevention of other diseases such as dementia, boxer dementia and Down syndrome. |