http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20100116765-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_745a75b0350f49480798ef5ab913bc0a |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5008 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate | 2009-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7f2a0fa3ded3d6230de23d9a01df0158 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_50877fa9689369de33abec162e57be2c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8ba00a71214e2ef6d487ac155bc1cb4 |
| publicationDate | 2010-11-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20100116765-A |
| titleOfInvention | Parkinson's disease treatment screening method |
| abstract | The present invention relates to a method for screening a drug for treating Parkin's disease, and more specifically, expresses a leucine rich repeat kinase 2 (LRRK2) mutant protein in a cell, adds an oxidative stress or mitochondrial toxic substance to the cell, and then Contacting the test substance to compare cells contacted with the test substance with cells not in contact with the test substance to determine whether cell death is reduced by contact of the test substance or transforming the test gene into the test gene And a method for screening Parkinson's disease therapeutic material screening kit by comparing the cells transformed with the test gene and cells not transformed with the test gene and measuring whether the cell death by the transformation of the test gene is reduced. It is about. According to the present invention, the compounds searched for in the present invention can be easily and economically searched for as a therapeutic agent for Parkinson's disease. The compounds searched for in the present invention can be used as a leading substance for treating Parkinson's disease. It can be used as a target gene for. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9695171-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9156845-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10039753-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9642855-B2 |
| priorityDate | 2009-04-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 971.