| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b73c0e74de8e59789728a49f9f56ff3a |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-31 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8125 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81 |
| filingDate |
2010-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d2d881556820581b1d066557bc67c85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_141964c3b0b2e0a1d810a9636f9dd403
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4daa1d602d15bbc013a6856110200b9e |
| publicationDate |
2010-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20100116558-A |
| titleOfInvention |
Protein or peptide fusions having increased body half-life by maintaining body persistence, and methods of increasing body half-life using the same |
| abstract |
The present invention relates to a protein or peptide fusion in which the half-life of the body is increased by maintaining the persistence in the body, and a method of increasing the half-life in the body using the same. Protein or peptide fusions according to the present invention, the blood half-life (T 1 / T 1 / by binding the bioactive protein or bioactive peptides to alpha-1 antitrypsin or alpha-1 antitrypsin variant mutated one or more amino acids to maintain body persistence 2 ) is significantly higher than the intrinsic bioactive protein or bioactive peptide, so the stability in the body is excellent. Thus, the protein or peptide fusions according to the present invention can be usefully used for the development of long-acting formulations of protein or peptide drugs. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101504824-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101460266-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EA-038110-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2013183948-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10561713-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2017003270-A1 |
| priorityDate |
2009-04-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |