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filingDate 2009-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06594e35ce06dfc8aef980ed078f2132
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publicationDate 2010-10-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-20100112385-A
titleOfInvention How to Determine Inflammatory Treatment
abstract The present invention relates to a method for determining the effect of treating inflammation, including causing inflammation in a test animal administered with a nonsteroidal anti-inflammatory drug candidate and measuring the concentration of a specific metabolite in urine. The method for determining the inflammatory therapeutic effect of the present invention is to (i) induce inflammation in a test animal administered with a candidate substance of the NSAID-based drug, and collect urine from the metabolite related to the inflammatory therapeutic effect contained in the urine. Measuring the concentration; And (ii) comparing the concentration of the metabolite contained in the urine with the concentration of the metabolite contained in the urine of the control group not administered the candidate material to determine whether the candidate material has an inflammatory treatment effect. Steps. By using the method of the present invention, it is possible to easily determine whether the candidate substance of the NSAID-based drug exhibits an inflammatory treatment effect in the new drug development step, and thus it will be possible to more effectively develop an NSAID-based drug exhibiting an inflammatory therapeutic effect.
priorityDate 2009-04-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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