http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20100100077-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69f43505d1b3ec31c224b32b5d1ec4e2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2009-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5f7e3d31149158930632c27f907ea6e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b18500ac31b9fecb68f659cda1e9f52a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a81a96ff66b05b2fdc19979467a48666 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4d2aa8de1fc47fa121597df91850eb22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12908f833165eee095ab9f0b8bef7fec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c34f01f4f058b7e5181010429bb93a16 |
| publicationDate | 2010-09-15-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20100100077-A |
| titleOfInvention | Method of screening materials with prophylactic or therapeutic activity for multiple sclerosis |
| abstract | The present invention comprises the steps of (a) treating the candidate substance to a protein (DRG2) having the amino acid sequence of SEQ ID NO: 1; And (b) measuring the change in activity of DRG2 obtained in step (a) and selecting a substance that increases the activity of DRG2, the method of screening for a substance having a prophylactic or therapeutic activity of multiple sclerosis. ; Or (a ') treating and culturing the candidate substance in cells overexpressing DRG2; And (b ') measuring the amount of DRG2 produced in the culture in step (a') and selecting a substance that increases the amount of DRG2 produced, the method of screening a substance having a prophylactic or therapeutic activity of multiple sclerosis. To provide. In addition, the present invention is a diagnostic kit for multiple sclerosis comprising a molecule capable of measuring the expression amount of a polynucleotide encoding DRG2, antibody, substrate, ligand, or cofactor (which the molecule specifically binds to the protein) cofactor); Or it provides a kit for diagnosing multiple sclerosis, which is a primer having a complementary sequence specific to the gene encoding the protein. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101421324-B1 |
| priorityDate | 2009-03-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 334.