http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20100099194-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2b071176d1f0558a78a2a65f85f5f523 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P15-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-90 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C233-43 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C237-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P5-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-26 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D211-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-66 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C237-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-43 |
filingDate | 2008-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_743dfe37d3caa4ef6c4df94705f20169 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_988028ac1d28e5ac1606dcc9ce1c4666 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12327af48a6084dc830e39767e01befb http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04385a1e0818c55ca2d26112047c6f72 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fd83814295c1deb0541a6ec24b4b38c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_be1b9fc4f2f5481c5d1a2f1769c91535 |
publicationDate | 2010-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | KR-20100099194-A |
titleOfInvention | Inhibitors of 17-beta-hydroxysteroid dehydrogenase |
abstract | The present invention relates to compounds of formula (I). Formula I In the above formula (I) R 1 , R 2 , R 3 , R 4 , R 5 , R 6 , R 7 , R 8 and R 9 are each independently (a) H; (b) R 13 , -OC (R 13 ) 3 , -OCH (R 13 ) 2 , -OCH 2 R 13 , -C (R 13 ) 3 , -CH (R 13 ) 2 or -CH 2 R 13 { Wherein R 13 is halogen}; (c) -CN; (d) optionally substituted alkyl, (e) optionally substituted heteroalkyl; (f) optionally substituted aryl; (g) optionally substituted heteroaryl; (h) optionally substituted arylalkyl; (i) optionally substituted heteroarylalkyl; (j) hydroxy; (k) alkoxy; (l) aryloxy; (m) -SO 2 -alkyl; And (n) -N (R 14 ) C (O) R 15 , wherein R 14 and R 15 are independently selected from H and hydrocarbyl, wherein (d), (e), ( Optional substituents of f), (h) and (i) are C 1-6 alkyl, halo, cyano, nitro, haloalkyl, hydroxy, C 1-6 alkoxy, carboxy, carboxyalkyl, carboxamide, mer Capto, amino, alkylamino, dialkylamino, sulfonyl, sulfonamido, aryl and heteroaryl; n and p are independently selected from 0 and 1, X is O, S, S = O, S (O) 2 , C = O, S (= O) 2 NR 16 , C = ONR 17 , NR 18 {where R 16 , R 17 and R 18 are independently Is selected from H and hydrocarbyl} R 10 is selected from H and hydrocarbyl, R 11 is selected from CR 19 R 20 , wherein R 19 and R 20 are independently selected from H and hydrocarbyl and C═O, R 12 is selected from a substituted 5- or 6-membered carbocyclic ring, said ring optionally containing one or more heteroatoms selected from N, S and O, said ring optionally having a further ring fused thereto, said at least one substituent Is selected from the hydrocarbyl group. |
priorityDate | 2007-11-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
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