| abstract |
The present invention provides selective inhibitors of the enzyme 11-beta-hydroxysteroid dehydrogenase type 1 (11β-HSD-1), 7-azaindole derivatives of formula (Ι), and metabolic syndrome, diabetes, insulin resistance, It relates to the use of such compounds for the treatment and prevention of obesity, lipid disorders, glaucoma, osteoporosis, cognitive impairment, anxiety, depression, immune disorders, hypertension and other diseases and abnormalities. |