abstract |
The present invention relates to compounds of formula (I), physiologically acceptable salts of these compounds and their N-oxides. The present invention also provides pharmaceutical compositions comprising at least one compound of formula (I) and / or at least one physiologically acceptable acid addition salt thereof, and additionally at least one compound of formula (I) or a physiologically acceptable acid of formula (I) disorders which advantageously respond to dopamine D 3 receptor antagonists or dopamine D 3 agonists, which method comprises adding administering a salt thereof to the dopamine D 3 receptor antagonists or dopamine D is of interest for the treatment of disorders to 3 agonist advantageously respond to It is about how to treat it. Formula I In the above formula (I) A is a saturated or unsaturated hydrocarbon chain having a chain length of 4 to 6 carbon atoms, said hydrocarbon chain being unsubstituted or substituted with 1, 2 or 3 methyl groups; R 1 is selected from the group consisting of hydrogen, C 1 -C 3 alkyl and fluorinated C 1 -C 3 alkyl; R 2 is hydrogen, halogen, cyano, C 1 -C 3 alkyl, C 1 -C 3 alkoxy, fluorinated C 1 -C 3 alkyl or fluorinated C 1 -C 3 alkoxy; R 3 is selected from the group consisting of branched C 4 -C 6 alkyl and C 3 -C 6 cycloalkyl; R 4 is C 1 -C 6 alkyl, C 3 -C 6 cycloalkyl, fluorinated C 1 -C 3 -alkyl and fluorinated C 3 -C 6 cycloalkyl. |