abstract |
The present invention is an effective inhibitor against DPP-IV, comprising novel enantiomers, diastereomers and racemates and having a β-amino group on the acyl chain, in free form, prodrug form or pharmaceutically acceptable salts. It relates to one 2-carbonyl-3-acyl-1,3-thiazolidine. The present invention also relates to pharmaceutical compositions comprising the disclosed compounds. The invention also relates to methods of making the disclosed compounds and to methods of treating DPP-IV mediated diseases. |