| abstract |
Combinations of PI3K inhibitor compounds represented by formula (I) and chemotherapeutic agents, including stereoisomers, geometric isomers, tautomers, metabolites and pharmaceutically acceptable salts thereof, are useful for the treatment of hyperproliferative disorders such as cancer. Also disclosed are methods of using said combinations for in vitro, in situ and in vivo diagnosis, prevention or treatment of such disorders or related pathological conditions in mammalian cells. |