| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_acb995eb22f9306adb4ab9027d8fda8f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2800-782
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61Q19-08
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K8-64
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K5-1024 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K5-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P17-00 |
| filingDate |
2008-10-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8c653be6480a50385a4a56e75848c751
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5eb313e986c1405913c3d43d41020a8b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bf513faea44988335f5abf0554b44593 |
| publicationDate |
2010-07-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20100083828-A |
| titleOfInvention |
Protective Skin Care Tetrapeptide |
| abstract |
The disclosed invention provides tetrapeptides having the amino acid sequence proline-glutamine-glutamate-X (P-Q-E-X), wherein X can be either lysine (K) or isoleucine (I). These tetrapeptides inhibit ultraviolet light (UV) -induced expression of pro-inflammatory cytokine interleukin-6 (IL-6) by skin epithelial cells and fibroblasts. Further, tetrapeptides can be derived from matrix metalloproteinase-1 (MMP-1) by dermal fibroblasts induced by direct exposure to UV light or by treatment with a medium under conditions with UV-treated keratinocytes. Suppresses upregulation. The small size and bio-activity of tetrapeptides provide those suitable for use as active ingredients in therapeutics and skin care products associated with inflammatory skin disorders. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2015174601-A1 |
| priorityDate |
2007-10-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |