| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_17c6c7da627b7bead7208250127b52c2 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2500-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-726 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6872 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-15
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-12 |
| filingDate |
2008-10-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71da34581581925f665041e8923db06d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c9d96c4d3236bf140c81906bc8d29364
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7ec05b7f721de68b656ddb309ec40cad
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2c113d9fdba619f21272461da36dde7e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c133be0d058fbdd59d31169d71611a81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c1c26c55d7b67402454c4cf91f72240c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7cc9e009772f7d67123e011c81ab9c44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_050c946857ea96bfce21987e119e896c |
| publicationDate |
2010-07-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
KR-20100080936-A |
| titleOfInvention |
Methods of identifying agents that modulate the activity of calcium-activated chloride channels |
| abstract |
The present invention provides a method for identifying a medicament that modulates the activity of a protein consisting of an amino acid sequence having at least 90% amino acid sequence identity with SEQ ID NO: 1 or SEQ ID NO: 1 and transporting chloride ions across a cell membrane, the method comprising: (a) Exposing the cell expressing the protein to the medicament; And (b) measuring the degree of chloride ion transport in the exposed cells, wherein a change in the degree of chloride ion transport compared to a control cell expressing the protein but not exposed to the drug is determined by the agent. It relates to an identification method characterized by indicating that the drug can regulate the activity of. Agents identified by this method can be used for the prevention or treatment of various diseases caused by dysfunction of calcium activated chloride channels. |
| priorityDate |
2007-10-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |