abstract |
The present invention discloses a mitochondrial-targeted antitumor agent, a method of making the mitochondrial-targeted antitumor agent and a method of using the mitochondrial-targeted antitumor agent for the treatment of diseases associated with unwanted cell proliferation. . In one aspect, the invention provides a composition having the formula: or a pharmaceutically acceptable salt thereof: AB, wherein A is a molecular chaperone inhibitor and B is a mitochondrial-penetrating moiety, and A and B are linked moieties It may or may not be connected by a tee. |