| abstract |
Provided herein is a spirocyclic aminoquinolone of Formula I and a composition containing the compound. The compounds and compositions provided herein are useful for the prevention, alleviation, or treatment of GSK-3 inhibitor mediated diseases. In formula (I), X 1 is O or NR 8 , A is a bond, or substituted or unsubstituted C 1 -C 2 alkylene, wherein if a substituent is present the substituents are 1-4 Q 2 is selected from group 2 , wherein Q 2 is alkyl or haloalkyl, p is 0 or 1 and q is an integer from 0 to 2. <Formula I> . |