http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20100062072-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_259045c6eba6e2c5d338b84e0a88b571 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D311-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-37 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D311-10 |
| filingDate | 2008-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c04da9136b7b3a691e329ef4a1e0d64e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc9fc851a0c1d5fc8895efcedcbc6c63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9eb39909fa3ea2662cc2e3a9583af6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e9b7e8e845e4810c51f7d9786fc0aab3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70b440834486c642eadb337e7b72708b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0a759d8484cc18229e90399b27b96dcd |
| publicationDate | 2010-06-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20100062072-A |
| titleOfInvention | Novel coumarin compound, preparation method thereof and pharmaceutical composition for inhibiting multi-drug resistance containing the same as an active ingredient |
| abstract | The present invention relates to a novel coumarin compound represented by the following formula (1), a method for preparing the same, and a pharmaceutical composition for inhibiting multi-drug resistance containing the same as an active ingredient, wherein the coumarin-based compound according to the present invention is a major cause of multi-drug resistance Inhibition of over-expression of phosphorus P-glycoprotein (Pgp) and increased anticancer activity when co-administered with anticancer drugs, can be used as a multi-drug resistant coping agent, treatment or modulator for anticancer drugs. By increasing the effect of cancer patients can increase the survival rate, and the dose of anticancer drugs administered in combination can reduce the side effects on normal cells can be useful in chemotherapy.n n n [Formula 1]n n n n n n n n (In Formula 1, R is as defined herein.) |
| priorityDate | 2008-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 24.