abstract |
Effective pain treatments are provided that last for a long time. An effective amount of clonidine can be administered to or around the target site, which can be used to relieve pain associated with surgery, as well as but not limited to spinal disc prolapse (ie, sciatica), spondylitis, stenosis, intervertebral back pain and arthralgia have. When a suitable formulation is provided in a biodegradable polymer, this relaxation can last for at least 3 days. In some instances, the remission may last for at least 25 days, at least 50 days, at least 100 days, at least 135 days, or at least 180 days. |