| abstract |
The present invention relates to compounds, pharmaceutical compositions and methods for the treatment and prevention of brain function deficiencies, which are useful for the treatment and prevention of brain function deficits, including the enhancement of receptor function of synapses in the brain neural networks responsible for basic and higher dimensional behavior. Brain neural networks, including respiratory control and cognitive function, are associated with memory impairment, resulting in an imbalance in neuronal activity between different brain regions, Parkinson's disease, schizophrenia, and hypoventilation. Abnormalities such as sleep apnea, attention deficit hyperactivity disorder, and mood swings, and associated with psychoactive substances, and respiratory abnormalities due to overuse of alcohol, anesthetics, analgesics, barbiturates, analgesics or neurotoxics, or drug symptoms Hypoventilation, eg central sleep apnea, stroke-derived sleep apnea, obstructive sleep apnea, central hypoventilation, obesity hypoventilation, infant sudden death syndrome, let's syndrome, spinal cord injury, traumatic brain injury, chain stoke Swelling, brings Ondin's curse, Prader-Willley syndrome, and drowning. In particular, the present invention relates to compounds useful in the treatment of such conditions and methods of using these compounds for such treatment. |