| abstract |
Novel dipeptide analogue compounds of formula (I), (II) or (III), or stereoisomers, tautomers, pharmaceutically acceptable salts, solvates or prodrugs thereof, which are inhibitors of factor XIa and / or plasma kallikrein, Containing compositions, and methods of their use, for example for the treatment or prevention of thrombotic disorders, are disclosed. <Formula I> <Formula II> <Formula III> |