abstract |
A catalyst composition for cross-coupling reactions containing a nickel metal source, a fluorine source, and a nitrogen-containing heterocyclic compound or phosphine compound of a specific structure is provided. In the presence of the catalyst composition, Formula 2: R 5 -MY 1 or Formula 3: R 5 -MR 5 (wherein R 5 is an aryl group, heteroaryl group, linear, branched or cyclic alkyl group) Or an organometallic compound represented by a linear, branched or cyclic alkenyl group, M represents an Mg atom or a Zn atom, and Y 1 represents a halogen group; and general formula 4: R 6 -Y 2 (Wherein R 6 represents an aryl group, a heteroaryl group, a linear, branched or cyclic alkyl group, or a linear, branched or cyclic alkenyl group, and Y 2 represents a halogen atom, methanesulfonate Group, a toluenesulfonate group or a trifluoromethanesulfonate group) is reacted to obtain a cross-coupling compound R 5 -R 6 with a high selectivity. |