abstract |
The present invention relates to a peptide capable of specifically targeting TNF-α-activated aortic endothelial cells and specifically targeting arteriosclerosis, and to a use thereof, more particularly represented by SEQ ID NO: 1 or SEQ ID NO: 2 The present invention relates to a peptide having an amino acid sequence and a composition for diagnosing, preventing and treating atherosclerosis comprising the same as an active ingredient, a composition for drug delivery comprising the same as an active ingredient, an imaging composition including the same as an active ingredient, and the like. Peptides of the invention can specifically bind to atherosclerotic sites. Therefore, the peptide of the present invention can be used for various purposes such as drug delivery to the atherosclerotic site, diagnosis, search and imaging of the atherosclerotic site. |