abstract |
The present invention relates to nucleic acid molecules comprising double stranded regions, and nucleic acid constructs encoding the same, useful for the treatment and / or prevention of influenza. In particular, the present invention relates to nucleic acid constructs encoding double stranded RNA molecule (s) that can be used to produce transformed poultry, such as chickens, which are less susceptible to avian influenza infection. The present invention also provides nucleic acid molecules comprising a double stranded region that can be used as a therapeutic agent for treating and / or preventing avian influenza, for example in poultry. |