| abstract |
The present invention relates to a composition for treating atopic dermatitis comprising Taxipoline 3-O-β-D-glucopyranoside isolated from Rhododendron root extract as an active ingredient. Taxifolin 3-O-β-D-glucopyranoside, an active ingredient of the composition of the present invention, significantly reduces the number of eosinophilic leukocytes (eosinophile), IL- While reducing levels of 4, 5, 13, while increasing the level of IL-10, promotes the expression of MBD-1, 2, 3, expression of COX-2 and iNOS has a potent inhibitory effect, atopy It can be developed as an immunomodulatory treatment for sexual dermatitis. In addition, the compound of the present invention is a natural compound purified from rhododendron root extract is very safe for the human body. |