Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7abafe538886c9684c458dec4d2d4725 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_69b4de7d64ebafc368b849bca94eab18 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0071 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-0083 |
classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12R1-85 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P13-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-52 |
filingDate |
2008-03-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_34bdac617a5913ec59c3378486eb7dc3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_60b9a3490f40a01c0fa374d26a960946 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_71def6f38c0b2669a7e0edb44479f33a |
publicationDate |
2010-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
KR-20100015868-A |
titleOfInvention |
Method for producing ceramide in transformed cells using sphingolipid Δ4-desaturase with endoplasmic reticulum signal |
abstract |
The present invention provides a method for producing humanoid ceramide in cells such as yeast cells. According to the production method of the present invention, 1) a endoplasmic reticulum is obtained by adding a nucleotide sequence encoding a yeast endoplasmic reticulum localization signal to the 3 'end of the sphingolipid Δ4-desaturase gene (DES1) by transformation of yeast cells. Introducing a sphingolipid Δ4-desaturase gene (DES1m) with a cargo signal; And 2) deleting the expression of the yeast sphinganine C4-hydroxylase gene (SUR2) by transformation of the yeast cells. |
priorityDate |
2007-03-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |