| abstract |
The present invention relates to a method for preparing cancer disease control antibodies using the novel screening paradigm. By isolating anticancer antibodies that use cancer cell cytotoxicity as an endpoint, the method enables the preparation of anticancer antibodies for therapeutic and diagnostic purposes. Antibodies can be used to aid in staging and diagnosis of cancer and can be used to treat primary tumors and tumor metastases. Anticancer antibodies can be conjugated to toxins, enzymes, radioactive compounds, and hematopoietic cells. |