| abstract |
The present invention relates to an oral pharmaceutical agent for delivering a drug to the colon, more specifically a core comprising at least a pharmaceutical excipient, an inner layer covering the core and comprising the drug, An oral pharmaceutical composition comprising an intermediate layer comprising a cationic polymer that coats the inner layer and is capable of dissolving or swelling at pH 6.6 or below, and an outer layer comprising an anionic polymer that coats the intermediate layer and is capable of dissolving at pH 7.0 or higher It relates to a formulation. |