http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20090117648-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f0e688f4f0f360c3093469970677fdbe |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1869 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82B1-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1857 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-1863 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82B1-00 |
| filingDate | 2009-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7bed544695080773a90775d34b716e3a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a106c89d12915c516809367104f1254 |
| publicationDate | 2009-11-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20090117648-A |
| titleOfInvention | Blood Brain Barrier Nanoparticles |
| abstract | The present invention provides a nanoparticle for passing the blood-brain barrier (BBB) comprising (a) an inorganic nanoparticle core and a water-soluble multifunctional organic ligand coated on the surface of the nanoparticle core and (b) ) Brain brain imaging composition and (c) brain-targeting pharmaceutical composition. The basic strategy adopted by the present invention is based on the discovery that the water-soluble multifunctional organic ligand coated on the nanoparticle core enables efficient blood brain barrier passage of the nanoparticles. When the inorganic nanoparticle core is coated with the water-soluble multifunctional organic ligand, it can efficiently cross the blood brain barrier without using a conventional adjuvant, and thus can be used as an effective brain imaging agent and drug delivery system to the brain. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101233439-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20200079679-A |
| priorityDate | 2008-05-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 432.