| abstract |
The present invention relates to a composite composition of a controlled release HMG-CoA reductase inhibitor and an angiotensin-II-receptor blocker, wherein each component is applied by applying the principle of pharmacological action at different times in the body. The present invention relates to a composite composition designed for controlled release at a specific rate, and is very effective in treating hypertension and preventing complications of those with metabolic syndrome in which diabetes, obesity, hyperlipidemia, and coronary artery disease are combined. It is about a method. More specifically, it is a drug delivery system designed to control and release a drug at a specific rate, so that it can have the most ideal effect when absorbed into the body, and the controlled release of HMG can maximize the effect even from external factors by increasing patient compliance. The present invention relates to a timed-dose complex composition of a -CoA reductase inhibitor and an angiotensin-II-receptor blocker. |