http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20090101278-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_143bc38b69048a023ae2b9ff9ae392e3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ef416fe4f66ebb1021cecfb0ba5ae45d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P33-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D403-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-02 |
| filingDate | 2007-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_36679d8ba4e418b65df235219680664e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_45c7bb57e397c1394df6baef88f127f0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d5c28098d2efcbd7950721f952e3c1b5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a2b702ab47a26c37878f46d7d82ff86a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2e15d0c913d28b2ffcc26c1bf2d8a53a |
| publicationDate | 2009-09-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20090101278-A |
| titleOfInvention | Azetidine analogs of nucleosidase and phosphorylase inhibitors |
| abstract | The present invention provides azetidine analogs or tautomers thereof, pharmaceutically acceptable salts, esters or prodrugs of nucleosidase and nucleoside phosphorylase inhibitors of formula (I), the use of these compounds as medicaments, Pharmaceutical compositions containing these compounds, methods of treating certain diseases using these compounds, methods of making these compounds, and intermediates useful in the preparation of these compounds:n n n n n n n n Wherein W and X are each independently selected from hydrogen, CH 2 OH, CH 2 OQ and CH 2 SQ; Y and Z are each independently selected from hydrogen, halogen, CH 2 OH, CH 2 OQ, CH 2 SQ, SQ, OQ and Q; Q is an alkyl, aralkyl or aryl group, each of which may or may not be substituted with one or more substituents selected from hydroxy, halogen, methoxy, amino or carboxy; R 1 is a radical of formula (II) or a radical of formula (III); A is selected from N, CH and CR 2 , wherein R 2 is selected from halogen, alkyl, aralkyl, aryl, OH, NH 2 , NHR 3 , NR 3 R 4 and SR 5 , and R 3 , R 4 and R 5 is an alkyl, aralkyl or aryl group unsubstituted or substituted with hydroxy or halogen, respectively, and when R 2 is alkyl, aralkyl or aryl, R 2 is unsubstituted or substituted with hydroxy or halogen; B is selected from hydroxy, NH 2 , NHR 6 , SH, hydrogen and halogen, wherein R 6 is an alkyl, aralkyl or aryl group unsubstituted or substituted with hydroxy or halogen; D is selected from hydroxy, NH 2 , NHR 7 , hydrogen, halogen and SCH 3 , wherein R 7 is an alkyl, aralkyl or aryl group unsubstituted or substituted with hydroxy or halogen; E is selected from N and CH; G is hydroxy or substituted by halogen, or unsubstituted or saturated or unsaturated ring C 1 -4 alkyl group, it does not exist. |
| priorityDate | 2006-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 477.