http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-20090093136-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_717c792fca7cc9c290c9db33e8fe078b |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-042 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-044 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1137 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N9-6472 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6893 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-00 |
| filingDate | 2008-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fe02d46749d5774695bee52cc8fc161d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c4e1f0aa5e9cfd156bc4419652f203c |
| publicationDate | 2009-09-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | KR-20090093136-A |
| titleOfInvention | A composition for screening anti-diabetic or anti-obesity material, a method for screening antiobesity material and a composition for preventing or treating diabetes or obesity using SENP2 |
| abstract | The present invention relates to a composition for screening an active substance for preventing or treating obesity, a screening method using the composition, and a composition for preventing or treating diabetes or obesity, and more specifically, a small-ubiquitin-like modifier (SUMO) specific protease 2 (SENP2) or a composition for screening an active substance for preventing or treating diabetes or obesity comprising a gene encoding SENP2 as a target material, a screening method using the same as a target material, and inhibiting the expression of a gene encoding SENP2, It relates to a composition for the prevention or treatment of diabetes or obesity comprising an agent that inhibits expression or activity. SENP2 used in the present invention dehydrates transcription factors such as PPARĪ³ and C / EBP family and increases their transcriptional activity, as well as is involved in the differentiation of adipocytes and the generation of adipose tissue. Screening methods are very useful for the identification of active substances for the prevention or treatment of diabetes or obesity-related diseases, and compositions of the invention comprising agents that inhibit the expression or activity of SENP2 are very useful for the prevention or treatment of diabetes or obesity. |
| priorityDate | 2008-02-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 512.