| abstract |
The present invention relates to a composition for preventing or treating cervical cancer comprising an inhibitor of Axl receptor tyrosine kinase (Axl) that regulates the expression of papilloma type 16 E6 gene causing cervical cancer, Human papilloma virus (HPV) type 16 E6 gene and the expression of Axl receptor tyrosine kinase revealed the tumor formation of cervical cancer and the possibility of establishing a method of inhibiting cervical cancer by the regulation of Axl receptor tyrosine kinase was derived. As a result, expression of the Axl receptor tyrosine kinase, which causes cervical cancer, can be controlled by antibodies, thereby increasing the expression of genes involved in carcinogenesis, increasing the sensitivity of natural killer cells, and also reducing the proliferation and metastasis of carcinogens. . |